产品货号：
Z16925
中文名称：
GDF8/Myostatin/MSTN抗体
英文名称：
Anti-GDF8/Myostatin/MSTN antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GDF8/Myostatin/MSTN antibody |
| 指标别名 | GDF 8;GDF8;MSTN;myostatin |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | MSTN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human GDF8/Myostatin/MSTN recombinant protein (Position:P20-S375). |
| 实际分子量 | 43KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Myostatin (also known as growth differentiation factor 8,abbreviated GDF-8) is a myokine,a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis:muscle cell growth and differentiation.In humans it is encoded by the MSTN gene.This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins.Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression.The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer.This protein negatively regulates skeletal muscle cell proliferation and differentiation.Mutations in this gene are associated with increased skeletal muscle mass in humans and other mammals. |
| Uniprot ID | O14793 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | myostatin |
| 蛋白名全称 | Growth/differentiation factor 8 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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